Aim: To prepare Boric acid glycerin (glycerite).
Requirements: Boric acid, Glycerin, Mortar and pestle, Beaker.
Theory: Glycerites are solutions or mixtures of medicinal substances in glycerin, containing not less than 50% by weight of glycerin. Most of the glycerites are vicious, while some have a jelly-like consistency. Glycerin is an important pharmaceutical solvent forming permanent and concentrated solutions. Boric acid reacts with glycerin and forms boro glycerin. The rate of formation of boro glycerin is directly proportional to heat, but it should not be heated above 150°C. This formulation is used as antiseptic as ear drops and throat paint.
|Boric acid||210 gm|
- Heat 8 gm of glycerin to the temperature of 140-150°C. Add boric acid and continuously heat with constant stirring until all the boric acid gets dissolved.
- Evaporate at a temperature not exceeding 150°C until the weight of the mixture has been reduced.
- Stir continuously and add a sufficient amount of warm glycerin to produce the required volume.
Storage: It is stored in a well-closed container.
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