Preparation of Glycerin Suppositories

Aim: To prepare and submit 100 ml Glycerin suppositories. 

Requirements: Glycerin, Sodium stearate, Purified water, Beaker, Glass rod, etc. 

Theory: A suppository is a solid dosage form that is inserted into the rectum (rectal suppository), vagina (vaginal suppository), or urethra (urethral suppository), where it dissolves or melts and exerts local or systemic effects. Suppositories are used to deliver both systemically and locally acting medications. 


IngredientsStandard formula 
Glycerin91 gm 
Sodium stearate9 gm 
Purified water5 gm 


  1. Heat the weighed amount of glycerin in a suitable container to about 120°C. 
  2. Dissolve sodium stearate in the heated glycerin with stirring. 
  3. Add purified water and mix. 
  4. Pour the hot mixture into the suitable suppository mold. 

Category: Local application. 

Storage: Preserve in a suitable container to protect from atmospheric moisture and temperature.

Make sure you also check our other amazing Article on : Types of Suppositories
Sharing Is Caring:

Leave a Comment