How To Make Herbal Toothpaste?

Aim: To prepare, evaluate and submit herbal toothpaste. 

Requirements: Soxhlet apparatus, Heating metal, Beaker, Mortar pestle, Guava leaves, and tubes. 

Chemicals: Ethanol, Papain Extract, Calcium carbonate, Sodium lauryl sulfate, Glycerin,  Methylcellulose, Sodium saccharine, Methylparaben, Propylparaben, Titanium dioxide,  Menthol, and Purified water. 

Formulation Consideration: Modern toothpaste formulations were developed in the 19th century. Later on, chalk and soap were incorporated into those formulations. After 1945, several formulation advancements of different detergents had begun; sodium lauryl sulfate had been used as an emulsifying agent. In recent years, the focus has shifted towards the release of active ingredients during formulation developments to prevent and/or treat oral illness. 

Toothpaste is a dentifrice used to clean, maintain and improve the health of teeth.  Toothpaste is mainly used to promote oral cleanliness and also acts as an abrasive that helps to prevent dental plaque and food particles from the teeth, aids in the removing and/or veiling of halitosis, and releases active ingredients such as fluoride to aid in preventing tooth and gum disease (e.g. Gingivitis). 


Sr.No.IngredientsQuantity Given (%)Quantity Taken
1Guava extract19.5  
3Calcium carbonate35 
4Sodium lauryl sulfate1.50 
6Methylcellulose0. 01.00  
7Sodium saccharine00.30  
10Titanium dioxide00.50  
12Purified waterq.s 


  1. Wash Guava leaves, and dry them under shade for 4 days. 
  2. Then ground the leaves to a fine powder and passed through Sieve No. 6. 
  3. Pack the powder in a soxhlet apparatus and extract for about 6 hours at 50°C with ethanol. 
  4. After the extraction process, collect the product and shade it dry for 10 days then powder the dry extract. 
  5. Formulate the standard toothpaste base.
  6. Incorporate powder extract of Guava leaves and papain in the base in concentrations as given in Table. 
  7. Fill the formulation in the toothpaste dispenser. 

Label: For external use only. 

Storage: Store in a cool dry place below 30°C. 

Packaging: In a collapsible tube of different sizes. 

Use: Whitens the teeth, fights cavities, and freshens breath. 

Directions: Brush the teeth thoroughly after each meal or at least twice a day with pea size amount of toothpaste. 

Precautions: Not to be swallowed. Keep out of reach of children. 

Evaluation Table: 

Sr.No.  TestObservations 
1Hard and sharp-edged abrasive particles  
3Spreadability (cm)  
4pH of 10% aq. suspension  
5Foaming ability  
6Cleaning ability 
Make sure you also check our other amazing Article on : How to Make Herbal Tooth Powder?
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