Aim: To prepare and submit liquid paraffin emulsion.
Requirements: Liquid paraffin, Vanillin, Benzoic acid solution, Methyl cellulose 20, Purified water, Chloroform, Sodium saccharin, Measuring cylinder, Mortar, and pestle.
Theory: Emulsions are two-phase systems in which one liquid is dispersed throughout another liquid in the form of small droplets. Liquid paraffin is a mineral oil that is not soluble in water. To make it soluble, methyl cellulose is used as an emulsifying agent. Benzoic acid and chloroform are used as preservatives, whereas sodium saccharin and vanillin are used as sweetening and flavoring agents.
Formula:
| Ingredients | Standard formula |
| Liquid Paraffin | 500 ml |
| Vanillin | 500 mg |
| Chloroform | 2.5 ml |
| Benzoic acid solution | 20 ml |
| Methyl cellulose 20 | 20 g |
| Sodium saccharin | 50 mg |
| Water | q.s. to 1000 ml |
Procedure:
- Heat about 120 ml of water until it boils and add methyl cellulose.
- When thoroughly hydrated, add a sufficient amount of water in the form of ice to produce 350 ml and stir until homogeneous.
- Mix chloroform and benzoic acid solution. Dissolve Vanillin in the mixture and add to methyl cellulose dispersion while stirring vigorously for 5 minutes.
- Add sodium saccharin dissolved in water and dilute to 500 ml with water.
- Add liquid paraffin, stirring constantly, and pass through a homogenizer, if required.
Category: Laxative.
Storage: Store in a well-closed container with having wide mouth and keep in a cool place. Do not be allowed to freeze.
Labeling: SHAKE WELL BEFORE USE
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