Aim: To prepare and submit 1000 ml of Magnesium hydroxide mixture.
Requirements: Mortar and pestle, Beaker, Glass rod, Magnesium sulphate, Sodium hydroxide, Light magnesium oxide, Chloroform, etc
Theory: Magnesium hydroxide is an inorganic compound with the chemical formula Mg(OH)2. It is a white solid with low solubility in water. Magnesium hydroxide mixture is an aqueous oral suspension of hydrated magnesium oxide. It may be prepared from a suitable grade of light magnesium oxide.
Formula:
| Ingredients | Standard Formula |
| Magnesium sulphate | 47.5 g |
| Sodium hydroxide | 15 g |
| Light magnesium oxide | 52.5 g |
| Chloroform | 2.5 ml |
| Purified water | Sufficient to produce 1000 ml |
Procedure:
- Dissolve sodium hydroxide in 150 ml of purified water. Add light magnesium oxide, and mix to form a smooth cream. Then add a sufficient amount of purified water to produce 250 ml.
- Pour this suspension into a solution of magnesium sulphate in 250 ml of purified water. Stir continuously during mixing.
- Allow the precipitate to subside. Remove the clear liquid, and transfer the residue to a calico strainer. Allow to drain and wash the precipitate with purified water until the washings give only a slight reaction for sulphates,
- Mix the washed precipitate with purified water. Dissolve chloroform in the mixture and add a sufficient amount of purified water to produce 1000 ml.
Category: Antacid, laxative, etc
Storage: Store in a tight container at a temperature above freezing and below 35°C.
Labelling: SHAKE WELL BEFORE USE
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