Preparation of Magnesium Hydroxide Mixture

Aim: To prepare and submit 1000 ml of Magnesium hydroxide mixture. 

Requirements: Mortar and pestle, Beaker, Glass rod, Magnesium sulphate, Sodium hydroxide, Light magnesium oxide, Chloroform, etc 

Theory: Magnesium hydroxide is an inorganic compound with the chemical formula Mg(OH)2. It is a white solid with low solubility in water. Magnesium hydroxide mixture is an aqueous oral suspension of hydrated magnesium oxide. It may be prepared from a suitable grade of light magnesium oxide. 


IngredientsStandard Formula 
Magnesium sulphate47.5 g 
Sodium hydroxide15 g 
Light magnesium oxide52.5 g 
Chloroform2.5 ml 
Purified waterSufficient to produce 1000 ml


  1. Dissolve sodium hydroxide in 150 ml of purified water. Add light magnesium oxide, and mix to form a smooth cream. Then add a sufficient amount of purified water to produce 250 ml. 
  2. Pour this suspension into a solution of magnesium sulphate in 250 ml of purified water. Stir continuously during mixing. 
  3. Allow the precipitate to subside. Remove the clear liquid, and transfer the residue to a calico strainer. Allow to drain and wash the precipitate with purified water until the washings give only a slight reaction for sulphates, 
  4. Mix the washed precipitate with purified water. Dissolve chloroform in the mixture and add a sufficient amount of purified water to produce 1000 ml. 

Category: Antacid, laxative, etc 

Storage: Store in a tight container at a temperature above freezing and below 35°C. 


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