Aim: To prepare and submit a strong Iodine solution I.P.
Requirement: Iodine, Potassium iodide, Alcohol 50%, Beaker, Glass rod, Measuring cylinder, etc.
Theory: The iodine is very slightly soluble in water. Its solubility can be increased by potassium iodide. Potassium iodide reacts with iodine to form polyiodide, which is more soluble in 50% alcohol. As the preparation is used internally as well as externally, 50% alcohol is used as a vehicle. Alcohols absorb heat from the body and get evaporated, thereby causing a cooling effect.
|Potassium iodide||6 ml|
|Alcohol 50% q.s.||100 ml|
Depending upon the quantity of preparation to be submitted, the working formula is calculated.
- Dissolve potassium iodide and Iodine in three fourth quantity of alcohol.
- Add a sufficient amount of alcohol to produce the required volume.
Storage: Store in a well-closed container and keep in a cool place. The material of the container should be resistant to iodine.
Labeling: FOR EXTERNAL USE ONLY
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