Preparation of Strong Iodine Solution I.P. 

Aim: To prepare and submit a strong Iodine solution I.P. 

Requirement: Iodine, Potassium iodide, Alcohol 50%, Beaker, Glass rod, Measuring cylinder, etc. 

Theory: The iodine is very slightly soluble in water. Its solubility can be increased by potassium iodide. Potassium iodide reacts with iodine to form polyiodide, which is more soluble in 50% alcohol. As the preparation is used internally as well as externally, 50% alcohol is used as a vehicle. Alcohols absorb heat from the body and get evaporated, thereby causing a cooling effect. 


IngredientsStandard formula
Iodine10 ml 
Potassium iodide6 ml 
Alcohol 50% q.s.100 ml 


Depending upon the quantity of preparation to be submitted, the working formula is calculated. 

  1. Dissolve potassium iodide and Iodine in three fourth quantity of alcohol. 
  2. Add a sufficient amount of alcohol to produce the required volume. 

Category: Antiseptic. 

Storage: Store in a well-closed container and keep in a cool place. The material of the container should be resistant to iodine. 


Make sure you also check our other amazing Article on : Preparation of Lugol’s Solution
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