Preparation of Calamine Lotion

Aim: To prepare and submit 100 ml of Calamine lotion. 

Requirements: Calamine, Zinc oxide, Bentonite, Glycerin, Liquid phenol, Sodium citrate,  Rose water, Butter paper, Analytical balance, Sieve, Mortar, and pestle. 

Theory: Lotions are liquid preparations meant for external use without friction. They are applied directly to the skin with the help of some absorbent material, such as cotton wool, and gauze soaked in it. Calamine lotion is a medication used to treat mild itchiness. This includes sunburn, insect bite, or other mild skin conditions. It may also help to dry out skin irritation. It is applied as a cream or lotion to the skin. 


IngredientsStandard formula
Calamine15 gm 
Zinc oxide5 gm 
Bentonite3 gm 
Liquid phenol0.5 gm 
Sodium citrate0.5 gm 
Glycerin5 ml 
Rose water100 ml 
Distilled water5 ml 


  1. Pass zinc oxide, bentonite, and calamine in the 40, 60 no. sieves separately. 
  2. Mix all the three in mortar and pestle. 
  3. Add glycerin dropwise and stir continuously in one direction. 
  4. Add sodium citrate and stir well. 
  5. Pour the required drops of liquified phenol. 
  6. Add some quantity of distilled water and stir well. 
  7. Make up the volume up to 100 ml with rose water or distilled water. 

Category: Protectant, Antimicrobial, Anti-acne Lotion. 

Storage: Store in a well-closed container and keep in a cool place. 


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